The clinical implications of adult-onset henoch-schonelin purpura
نویسندگان
چکیده
Henoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens.
منابع مشابه
Henoch-Schonlein purpura with multiple symptoms in adult patient: a case report
Background: Henoch-Schonlein purpura is a common systemic vasculitis in childhood, usually characterized by skin, abdominal, and renal manifestations. Most patients are 4 to 7 years old and are more common in boys. The disease is very rare in adults with multiple symptoms. Case Report: A 20-year-old male patient with final diagnosis of Henoch-Schonlein disease with rare complications was admitt...
متن کاملSuccessful treatment of severe gastrointestinal involvement in adult-onset Henoch-Schönlein purpura.
Henoch-Schönlein purpura is a small vessel vasculitis which is uncommon in adults. The presentations of adult-onset disease are different from those seen in childhood. The commonly-recognised serious gastrointestinal complications of childhood are less well-documented in adults. We report three cases of adult-onset Henoch-Schönlein purpura with severe gastrointestinal involvement. All were men,...
متن کاملAnalysis and follow up on 28 cases of henoch- schonlein purpura at Gheam children's hospital in the city of Hamedan
To determine clinical presentation and outcomes of henoch schonlein purpura, 28 cases of the disease who were admitted in our hospital during a period of 7.5 years, were studied through review of their hospital records. Their mean age was 7.5 years, and matel female ratio was 1.5. the characteristic skin rash of syndrome was present in all of the cases. The prevalence of the other main manifest...
متن کاملA Case Report of Hodgkin's lymphoma with Early Manifestation of Henoch-Schonlein Purpura in a Child
Hodgkin's lymphoma is one of the most common types of lymphoma among children, usually characterized by persistent head and neck adenopathies that are unresponsive to antibiotic treatment. In rare cases, the primary manifestation of this malignancy includes paraneoplastic, immunological, and vasculitic syndromes in children. Here, we introduce a 13-year-old boy, and Hodgkin's lymphoma was initi...
متن کاملAdult-Onset Henoch-Schonlein Purpura Duodenitis
Henoch-Schonlein purpura (HSP) is an immune-mediated vasculitis. HSP presents with purple spots on the skin (purpura), arthralgia, digestive problems, and kidney injury. HSP is most commonly seen in children, and rarely presents in adults. The pathogenesis involves the deposition of immune complexes in small to medium size blood vessels which leads to necrosis and inflammation. Most patients re...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 9 شماره
صفحات -
تاریخ انتشار 2011